Odesláno z mého bezdrátového zařízení BlackBerry®
From: "UKidney.com" <info@ukidney.com>
Date: Tue, 20 Dec 2011 14:57:56 -0500
To: Roman Kantor<ledviny.cz@gmail.com>
ReplyTo: UKidney Staff <info@ukidney.com>
Subject: BREAKING: No benefit of Aliskiren added on to ACE or ARB: a Disappointing development
No benefit of Aliskiren added on to ACE or ARB: a disappointing development
In a stunning development, Novartis said Tuesday that it will terminate the late-stage ALTITUDE study investigating Rasilez (aliskiren) in patients with type 2 diabetes and renal impairment on the recommendation of an independent data monitoring committee. The company indicated that the committee concluded that "patients were unlikely to benefit" from the addition of Rasilez to standard anti-hypertensives and also identified higher adverse events in this group (source: FirstWord).On a personal and professional note, these results come as a great disappointment to me. Not only does it suggest no further protection for our patients prescribed this strategy in an effort to reduce the burden of cardiorenal disease, but I was a great believer in the hypothesis and taught about it extensively throughout my career.
Read more here
10.1.12: Aktualizace: odkaz na dopis, který nedoporučuje kombinovat přípravek Aliskiren s ACE-i nebo AT1 blokátorem: SUKL
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